Complex

From ReactomeWiki

A physicalEntity formed by the association of two or more other entities (which can themselves be complexes), which are its components. To create a valid complex instance, at least one component must be specified. Even if an entity is known to be composed of subunits, unless the subunits that allow it to be distinguished from other cellular entities can be identified, it cannot be annotated as a complex. Instead it must be an otherEntity (e.g., a generic bit of heterochromatin, or a lipid raft). However, complex instances can legitimately be created in cases in which experimental data suggest that additional subunits remain to be identified or that the stoichiometry of the complex is uncertain. Examples: A complex: Presenilin homodimer \[plasma membrane\] ([24]) A complex assembled from other complexes: pyruvate dehydrogenase complex \[mitochondrial matrix\] ([25]) A complex with several known subunits but uncertain complete composition and stoichiometry: GPI-N-acetylglucosaminyltransferase ([26])