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Welcome to the Reactome Wiki

Reactome Homepage

Saturday, 17 November 2018

Reactome is an online bioinformatics database of human biology described in molecular terms. It is an on-line encyclopedia of core human pathways - DNA replication, transcription, translation, the cell cycle, metabolism, and signaling cascades - and can be browsed to retrieve up-to-date information about a topic of interest, e.g., the molecular details of the signaling cascade set off when the hormone insulin binds to its cell-surface receptor, or used as an analytical tool for the interpretation of large datasets like those generated by DNA microarray analysis. The information in Reactome is provided by expert biologists and gathered from the published research literature. Each module is peer-reviewed before it is publicly released on the Reactome website, and is periodically updated.

This wiki is part of our online documentation and curation resources. Use the navigation bar above to access our user guides and documentation.We also ask that you help us keep our documentation as clear, up-to-date, and useful as possible. You are welcome, in fact, invited to refine our documentation. Please read through the highlighted section below and consider filling out the form to become a registered Reactome wiki user.

Reactome is updated on a quarterly schedule, with each release we will review changes that have occurred in our User's Guide and package these changes into the release version of the guide.

If you have a question, you might want to check our FAQ.

If you have comments, suggestions, or questions not covered in the FAQ, please contact us at


ReactomeWiki is an open resouce availble to all. There are lots of ways you can help improve ReactomeWiki:

  • Add your knowledge to existing pages
  • Add new pages about topics you're interested in
  • Add links
  • Fix errors

ReactomeWiki members can use ReactomeWiki in ways that are not available to unregistered users. Read more about user accounts at ReactomeWiki membership. Apply for an account by going to our Accounts page! Please email the Reactome Team at if you have any questions!

As of today the Reactome Wiki houses 91 articles, using 1,012 pages, maintained by 133 users, whom have edited these pages 7,391 times.